American Board of Internal Medicine (ABIM) Certification Practice Exam

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Prepare for the ABIM Certification Exam with multiple choice questions and detailed explanations. Strengthen understanding with flashcards, hints, and thorough review materials. Ace your test!

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What is the typical baseline hemoglobin level in persons with sickle cell disease (Hb SS)?

8 to 10 g/dL
10 to 12 g/dL
6 to 7 g/dL
4 to 5 g/dL

The correct answer is: 6 to 7 g/dL

Individuals with sickle cell disease (Hb SS) generally have a baseline hemoglobin level that is lower than the normal range due to the chronic hemolytic anemia associated with the disease. This anemia results from the destruction of sickle-shaped red blood cells, which have a shorter lifespan compared to normal red cells. The typical baseline hemoglobin level for patients with Hb SS usually falls between 6 to 8 g/dL. Therefore, the range of 6 to 7 g/dL aligns with what is commonly observed in this population, accurately reflecting their condition. Hemoglobin levels tend to fluctuate in these patients, influenced by factors such as pain crises, infections, and other health stresses, but the baseline range remains consistently low, highlighting the need for ongoing management and monitoring.