American Board of Internal Medicine (ABIM) Certification Practice Exam

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What types of medications are used in the supportive treatment of stress cardiomyopathy?

  1. ACE inhibitors and Angiotensin II blockers

  2. Calcium channel blockers and Diuretics

  3. β-blockers and ACE inhibitors

  4. Statins and Antiplatelet agents

The correct answer is: β-blockers and ACE inhibitors

In the supportive treatment of stress cardiomyopathy, β-blockers and ACE inhibitors play a vital role. Stress cardiomyopathy, also known as takotsubo syndrome, often presents with symptoms similar to those of a myocardial infarction, and the management focuses on supportive care tailored to the patient's hemodynamic status. β-blockers are essential in this context as they help manage sympathetic nervous system activation, which can be significantly heightened in cases of stress cardiomyopathy. By blocking the effects of adrenaline, β-blockers reduce heart rate and myocardial oxygen demand, which can be particularly beneficial as the heart is vulnerable during this condition. ACE inhibitors contribute to the management by addressing fluid overload, controlling blood pressure, and reducing afterload. This class of medications can also help in the recovery of cardiac function by promoting better hemodynamics, preventing further strain on the heart muscle. In terms of the other options provided, while calcium channel blockers and diuretics have their roles in cardiovascular disease management, they are not the primary or suggested medications for stress cardiomyopathy specifically. Additionally, although statins and antiplatelet agents serve critical functions in various cardiovascular ailments, they are not standard treatments for stress cardiomyopathy itself.